济宁市第一人民医院-内科学-石书龙

发布者:临床医学院附属医院发布时间:2025-07-22浏览次数:15


  • 基本情况介绍:

石书龙,中西医结合临床医学博士,药学博士后,2022年济宁市中医药人才“金银花”项目中医药中青年骨干人才;2023年被山东省卫生健康委、山东省人力资源和社会保障厅评选为“齐鲁扁仓杰出青年人才”;济宁医学院山东第一医科大学硕士研究生导师;济宁市“圣地人才一卡通”获得者;《Frontiers in molecular biosciences》、《Frontiers in endocrinology》 、《Heliyon》等期刊杂志特约审稿专家;济宁市第一人民医院内分泌科中西医结合亚专科学科带头人,在我科率先开展多项中西医结合治疗操作。

  • 研究方向:

内分泌代谢性疾病的诊疗

  • 研究生培养:

目前指导研究生1

  • 年承担科研课题:

序号

立项编号

项目名称

起止年月

经费(万元)

1

SDCX-ZG-202302036

基于网络药理学、代谢组学与肠道微生态联合探讨葛根解毒方治疗 2 型糖尿病合并乳腺癌的药理机制

2023-06 2025- 05

5

2

Q-2022026

基于系统生物学、代谢组学与肠道微生态联合探讨金芪降糖片改善胰岛素抵抗的作用机制

2022-08 2024- 07

4

3

2024YXNS169

基于孟德尔随机化和多组学分析探讨姜黄素通过诱导铁死亡、重塑巨噬细胞极化及改善代谢重编程治疗肺腺癌的作用机制

2024-12 2026- 12

2

...






  • 年发表的主要论文:

Shi shulong, Tian X, Gong Y, Sun M, Liu J, Zhang J, Liu Y, Li L, Jiang S. Pivotal role of JNK protein in the therapeutic efficacy of parthenolide against breast cancer: Novel and comprehensive evidences from network pharmacology, single-cell RNA sequencing and metabolomics. Int J Biol Macromol. 2024 Nov;279(Pt 3):135209.(第一作者)


Xia Z, Shi shulong, Ma X, Li F, Li X, Gaisano HY, Zhao M, Li Y, He Y, Jiang J. Mediating effect of adiponectin between free fatty acid and tumor necrosis factor-α in patients with diabetes. Nutr Diabetes. 2024 Jun 17;14(1):45. (共同一作)


Tian X, Liu F, Zhao J, Liu Q, Wang H, Liu Y, Zhang J, Zhang Y, Yang Y, Shi shulong, Jiang S. Mechanism and molecular targets of Euphorbia fischeriana Steud root extract in hepatocellular carcinoma. J Ethnopharmacol. 2025 Apr 25;346:119707.(共同通讯)


Shi shulong, Zhao S, Tian X, Liu F, Lu X, Zang H, Li F, Xiang L, Li L, Jiang S. Molecular and metabolic mechanisms of bufalin against lung adenocarcinoma: New and comprehensive evidences from network pharmacology, metabolomics and molecular biology experiment. Comput Biol Med. 2023 May;157:106777. (第一作者)


Shi shulong, Sun M, Liu Y, Jiang J, Li F. Insight into Shenqi Jiangtang Granule on the improved insulin sensitivity by integrating in silico and in vivo approaches. J Ethnopharmacol. 2022 Jan 10;282:114672. (第一作者)


Liu F, Li L, Zhang Y, Zhang J, Tian X, Zhang D, Zhang N, Yan T, Shi shulong, Wu J, Jiang S. Mechanistic Exploration of Shugan Jianpi Formula for Treating Triple-Negative Breast Cancer Under Chronic Stress: A Network Pharmacology-Guided Experimental Study. Drug Des Devel Ther. 2025 May 31;19:4585-4603.(共同通讯)


Gong Y, Tian X, Ma X, Xing J, Ji Z, Gao X, Chen Z, Hu F, Yin D, Li F, Sheng C, Liu Y, Shi shulong. New insights into the pharmacological mechanisms of Jinqi Jiangtang Tablets in the treatment of type 2 diabetes mellitus: A multi-omics approach combined with experimental validation. J Ethnopharmacol. 2025 May 29;350:120020. (通讯作者)