济宁医学院附属医院-儿科学-王化彬

• 基本情况介绍：

王化彬，儿科学博士，博士后，山东省高层次人才，硕士研究生导师，济宁医学院附属医院NICU副主任，济宁市新生儿医疗质量控制中心副主任，济宁市儿童重症感染防治重点实验室学术带头人。兼任海峡两岸医药卫生交流协会新生儿学专业委员会委员、中国医药教育协会儿童健康促进专委会委员、山东省医师协会围产医学大数据专业委员会委员、山东省医学会儿科分会学术发展学组委员、山东省医学会儿科分会感染学组委员、济宁市医学会儿科青年分会副主任委员等。近5年以第一/通讯作者发表SCI论文15篇。主持山东省自然科学基金1项，省博士后创新人才支持计划1项，市重点研发计划1项，入选中青年医师海外人才培养项目（英国）。担任PediatricDiscovery青年编委。

• 研究方向：

新生儿败血症

• 研究生培养：

在读研究生4人

• 近五年承担科研课题：

序号	立项编号	项目名称	起止年月	经费（万元）
1	ZR2023QH382	m6ARNA甲基化阅读器IGF2BP1在新生儿败血症中的作用与机制研究	2024.01-2026.12	37.5
2	JYFY321211	RNA2'-O-甲基转移酶 FBL在儿童脓毒症肺损伤时对肺泡巨噬细胞极化调控的机制研究	2022.08-2024.07	100
3	LCYJ-021	基于机器学习算法的早产儿化脓性脑膜炎风险预测模型的开发与验证	2025.2-2028.2	14.9
4	2024-BS-004	基于单细胞测序技术的新生儿败血症固有免疫应答的可视化及调控机制解析	2025.1-2027.12	78.6

• 近五年发表的主要论文：

以第一作者首位发表SCI论文：

1. WangH, Yang R, Chen N, Li X. Heterogeneity of Neutrophils andImmunological Function in Neonatal Sepsis: Analysis of MolecularSubtypes Based on Hypoxia - Glycolysis - Lactylation. MediatorsInflamm. 2025;2025:5790261.

2. WangH, Zhang R, Xu J, Zhang M, Ren X, Wu Y. Development of a PrognosisPrediction Model for Pediatric Sepsis Based on the NLPR. J InflammRes. 2024;17:7777 - 7791.

3. WangH, Chen X, Shen C, et al. Value of cardiac enzyme spectrum for therisk assessment of mortality in critically ill children: a single -centre retrospective study. BMJ Open. 2024;14(10):e074672.

4. WangH, Guo C, Wang Y, Li C, Wu Y, Ren X. Immune cell composition and itsimpact on prognosis in children with sepsis. BMC Pediatr.2024;24(1):611. doi:10.1186/s12887 - 024 - 05087 - 1

5. WangH, Huang J, Guo C, et al. Molecular subtypes based on N6 -methyladenosine RNA methylation demonstrate the heterogeneity ofimmune and biological functions in pediatric septic shock. Heliyon.2023;9(10):e20714.

6. WangH, Chang Y, Xin M, et al. Hypothermia or hyperthermia, which isassociated with patient outcomes in critically ill children withsepsis? - A retrospective study. BMJ Open. 2023;13(4):e067716.

7. WangH, Huang J, Yi W, et al. Identification of Immune - Related KeyGenes as Potential Diagnostic Biomarkers of Sepsis in Children. JInflamm Res. 2022;15:2441 - 2459. doi:10.2147/JIR.S359908

8. WangH, Liang R, Liang T, et al. Effectiveness of Sodium BicarbonateInfusion on Mortality in Critically Ill Children With MetabolicAcidosis. Front Pharmacol. 2022;13:759247.

9. WangH, Huang J, Jin X, et al. Hypermagnesaemia, but Not Hypomagnesaemia,Is a Predictor of Inpatient Mortality in Critically Ill Childrenwith Sepsis. Dis Markers. 2022;2022:3893653.

10. WangH, He Z, Li J, et al. Early Plasma Osmolality Levels and ClinicalOutcomes in Children Admitted to the Pediatric Intensive Care Unit:A Single - Center Cohort Study. Front Pediatr. 2021;9:745204.

11. WangH, Huang J, Liao W, et al. Prognostic Value of the Red CellDistribution Width in Patients with Sepsis - Induced AcuteRespiratory Distress Syndrome: A Retrospective Cohort Study. DisMarkers. 2021;2021:5543822.

12. WangH, Zhang L, Liao W, et al. Hyperphosphatemia rather thanhypophosphatemia indicates a poor prognosis in patients with sepsis.Clin Biochem. 2021;91:9 - 15.

13. WangH, Yin Y, Wang R, et al. Clinicopathological features, risk andsurvival in lung cancer survivors with therapy - related acutemyeloid leukaemia. BMC Cancer. 2020;20(1):1081. Published 2005.

• 近五年获奖情况：

1.2023年2年获山东惠才卡（直接颁发类）

2.2022年11月获山东省博士后创新人才支持计划

联系方式：

邮箱：wanghb53@mail2.sysu.edu.cn