第960医院-临床病理-李培峰

发布者：临床医学院附属医院发布时间：2025-07-25浏览次数：10

  • 基本情况介绍：

李培峰，男，1981年3月生，中共党员，博士，副主任医师，副教授，硕士生导师。兼任中国研究型医院学会超微与分子病理学专委会委员、山东省医师协会临床病理医师分会常务委员、山东省医学会病理学分会青年委员和学术发展学组委员等。


  • 研究方向：从事肿瘤分子病理学研究，主要研究方向为碘难治性甲状腺癌发病机制以及甲状腺癌淋巴结转移分子机制。


  • 研究生培养：培养锦州医科大学、山东中医药大学硕士研究生8名，其中1名研究生2次获得国家奖学金。


  • 近五年承担科研课题：

序号

立项编号

项目名称

起止年月

经费（万元）

1

ZR2023MH029

甲状腺癌 BRAF/TERT突变协同促进碘耐药的分子机制

2024.1-2026.12

10

2

202201041061

BRAF/TERT共突变协同抑制NIS胞膜定位影响PTC碘摄取的研究

2023.1-2024.12

10

3

202019024

甲状腺癌转移相关lncRNA验证及分子机制初步研究

2021.1-2023.12

10

4

CBSKL2019ZDKF02

原发性胃肠弥漫大B细胞淋巴瘤分子遗传学突变特征及发病机制初步研究

2019.7-2020.12

20


  • 近五年发表的主要论文：

  1. RuijingLiu, Jian Zhu, Beibei Jiang, Yinan Hu, Jingli Xue, Wen Liu, YiqiangYin, Yuqing Wei, Zhidong Sun, PeifengLi(corresponding author). Clinicopathological and molecularcharacteristics of papillary thyroid carcinoma with BRAF V600E andTERT promoter co-mutations. Pathology - Research and Practice. 2025,272: 156112.

  2. YuqingWei, Yan Cao, Wen Liu, Zongjing Zhang, PeifengLi (correspondingauthor).Ovarian high-grade follicular thyroid carcinoma with teratoma andNRAS mutation in an adolescent female: A case report. Pathology -Research and Practice. 2025, 272: 156076.

  3. RuijingLiu, Wen Liu(co-firstauthor),Jingli Xue, Beibei Jiang, YuQing Wei, Yiqiang Yin, PeifengLi(correspondingauthor).LncRNAs associated with lymph node metastasis in thyroid cancerbased on TCGA database. Pathology - Research and Practice. 2024,256: 155255.

  4. WenLiu, Beibei Jiang, Jingli Xue, Ruijing Liu, Yuqing Wei, PeifengLi (correspondingauthor).Clinicopathological features of differentiated thyroid carcinoma aspredictors of the effects of radioactive iodine therapy. Annals ofDiagnostic Pathology. 2024, 69: 152243.

  5. RuijingLiu, Jingli Xue, Wen Liu, Beibei Jiang, Fuyun Shi, Zhenzheng Wang,PeifengLi(corresponding author).Case report: Osteosarcomatous differentiation in the lung metastasisof a malignant phyllodes tumor. Front Med. 2023, 10:1141353.

  6. JianZhu, Changrui Liu, Dan Wang, Xianjiao Cao, Shuai Wang, Yixin Liu,Jun Wang,Peifeng Li(correspondingauthor),Qingqing He. The emerging landscapes of long noncoding RNA inthyroid carcinoma: biological functions and clinical significance.Front Oncol. 2021; 11: 706011.

  7. PengZhou, QingqingZhang, JianZhu, PeifengLi(correspondingauthor). Molecularcharacterization of pleomorphic liposarcomatous differentiation inmalignant phyllodes tumor of the breast: A case report. Pathol ResPract.2021; 224: 153489.

  8. PeifengLi,Jia Chai, Zi Chen, Yang Liu, Jie Wei, Yixiong Liu, Danhui Zhao, JingMa, Kaijing Wang, Xia Li, Yang Shao, Li Gong, Wei Zhang, ShuangpingGuo, Qingguo Yan, Mingyang Li, Linni Fan, Zhe Wang. Genomic MutationProfile of Primary Gastrointestinal Diffuse Large B-Cell Lymphoma.Front Oncol. 2021; 11: 622648.

  9. JunpengXu, Peifeng Li(co-first author),Jia Chai, Kangjie Yu, Tianqi Xu, Danhui Zhao, Yixiong Liu, YingmeiWang, Kaijing Wang, Jing Ma, Linni Fan, Qingguo Yan, Shuangping Guo,Hualang Xiao, Qilin Ao, Zhaoming Wang, Weiping Liu, Sha Zhao, WeihuaYin, Yuhua Huang, Yaqin Li, Miaoxia He, Rong Liang, Mingyang Li, ZheWang. The clinicopathological and molecular features of sinusoidallarge B-cell lymphoma. Mod Pathol. 2021; 34(5):922-933.

  10. KangjieYu, PeifengLi (co-firstauthor), TianqiXu, JunpengXu, KaijingWang, JiaChai, DanhuiZhao, YixiongLiu, YingmeiWang, JingMa, LinniFan, ShuangpingGuo, ZengshanLi, MingyangLi, ZheWang. Decreased infiltration of CD4+ Th1 cells indicates a goodresponse to ursodeoxycholic acid (UDCA) in primary biliarycholangitis. Pathology - Research and Practice. 2021; 217:153291.

  11. PeifengLi, Mingyang Li,Kaijing Wang, Yixiong Liu, Yingmei Wang, Danhui Zhao, Jia Chai, JingMa, Xia Li, Jie Wei, Linni Fan, Feng Zhang, Jing Ye, Qingguo Yan,Shuangping Guo, Zhe Wang. Genetic alterations in cell cycleregulation-associated genes may promote primary progression ofgastrointestinal stromal tumors. Laboratory Investigation. 2020;100(3): 426-437.

  12. 魏于清，刘稳，刘瑞静，刘晓红，李培峰（通讯作者）.胸腺非典型类癌进展为具有高核分裂象计数的非典型类癌1例.临床肿瘤学杂志，2025，30(4):414-416.

  13. 薛景丽，刘瑞静，刘稳，魏于清，姜贝贝，尹义强，李培峰（通讯作者）.长链非编码RNADPP10-AS1促进甲状腺乳头状癌淋巴结转移的机制研究.重庆医学，2025，54(5):1066-1073，1079.

  14. 姜贝贝，尹义强，刘瑞静，刘稳，薛景丽，李敏，李培峰（通讯作者）.碘难治性甲状腺乳头状癌的基因突变特征.临床与实验病理学杂志，2025，41(1)：37-43.

  15. 姜贝贝，李帅，刘稳，薛景丽，李敏，李培峰（通讯作者）.放射性碘难治性分化型甲状腺癌的临床病理特征.重庆医学，2024，53(1):11-16.

  16. 曹瑞雪，朱伟杰，彭兆辉，于国丽，李培峰（通讯作者）.具有细胞多形性和微囊形成的中分化松果体实质肿瘤1例并文献复习.诊断病理学杂志，2022，29(7)：650-654.

  17. 曹瑞雪，陈鑫，姜贝贝，李培峰（通讯作者）.细支气管腺瘤1例.临床与实验病理学杂志，2021，37(3)：368-369.

  18. 姜贝贝，刘晓红，曹瑞雪，于国丽，李培峰（通讯作者）.油红O染色在甲醛固定的乳腺富于脂质癌中的实践应用.临床与实验病理学杂志，2021，37(3)：359-360.